In short: Margin = profit ÷ selling price. Markup = profit ÷ purchase price. With a purchase price of €20 and a net sale of €30, markup is 50% and margin about 33%.
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Margin = markup ÷ (1 + markup). A markup of 100% equals a margin of 50%.
Many say “margin” and mean markup. Then prices and profit do not match. Always calculate with the net price and deduct shipping, fees, advertising and returns before you talk about profit.
It depends on the industry and ad costs. What matters is that profit remains after all costs.
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